Incidence of cancer among workers exposed to vinyl chloride in polyvinyl chloride manufacture. Unfortunately, PVC can also harm people's health. Air Toxics Hot Spots Program Technical Support Document for Cancer Potencies. Polyvinyl chloride – also known as PVC or vinyl – has become an intrinsic part of our lives ever since the early-mid 20th century. Vinyl chloride, a chemical known to cause cancer, poisons the air breathed by workers and people living in contaminated communities. * Bis(2-ethylhexyl)Phthalate is a NTP anticipated human carcinogen and IARC possible human carcinogen. ... Manufacturers use vinyl chloride to produce polyvinyl chloride, or PVC. Polyvinyl chloride (PVC) is one of the most commonly manufactured plastics in the world, used in a wide variety of products including packaging, pipes, automotive parts, construction materials and furniture. Development of oral cancer tissue-mimicking phantom based on polyvinyl chloride plastisol and graphite for terahertz frequencies Tianmiao Zhang , a, b, * Ravshanjon Nazarov , a Alexey P. Popov , c Petr S. Demchenko , a Alexander V. Bykov , c Roman O. Grigorev , a Anna V. Kuzikova , a Victoria Y. Soboleva , a Dmitry V. Zykov , a Igor V. Meglinski , c, d, e and Mikhail K. Khodzitskiy a It is flammable (burns easily) as a gas and is not stable at high temperatures. POLYVINYL CHLORIDE LATEX may become discolored may on exposure to heat or light in the absence of stabilizers (NTP, 1992). CNC Machining: Polyvinyl Chloride can be cut on a CNC machine but any machinist who has tried has probably experienced degradation in the cutter depending on the material it is made from. Chloroethene, Chloroethylene, Ethylene monochloride, Monochloroethene, Monochloroethylene, VC, VCM, Vinyl chloride monomer (VCM) Colorless gas or liquid (below 7°F) with a pleasant odor at high concentrations. 2008 law banning phthalates from children's toys does not cover the PVC in school supplies. It has both industrial and household uses. (Polyvinyl Chloride contains less than 1% by weight)** Vinyl Chloride Monomer is an OSHA cancer suspect agent, ACGIH confirmed human carcinogen, and NTP and IARC human carcinogen. Polyvinyl chloride is more often referred to by its less-technical names, PVC and vinyl. Vinyl chloride is a deadly toxic chemical, despite industry’s repeated attempts to hide the threats. The results of a follow up study of the incidence of cancer and the mortality in a cohort of 454 male workers producing vinyl chloride and polyvinyl chloride are presented. Results: In PVC baggers exposed to high levels of respirable PVC particles in the workplace, the lung cancer OR increases by 20% for each extra year of work (OR = 1.2003; 95% CI 1.0772 to 1.3469; p = 0.0010), when the influence of age and smoking habits is controlled. Angiosarcoma of the Liver Among Polyvinyl Chloride Workers -- Kentucky. Appendix B. Chemical-specific summaries of the information used to derive unit risk and cancer potency values. Breathing high levels of vinyl chloride for short periods of time can cause dizziness, sleepiness, unconsciousness, and at extremely high levels can cause death. Polyvinyl chloride (PVC) is a widely used building material praised for its durability, yet criticized for its potential health hazards. Polyvinyl Chloride Economical, versatile polyvinyl chloride (PVC, or vinyl) is used in a variety of applications in the building and construction, health care, electronics, automobile and other sectors, in products ranging from piping and siding, blood bags and tubing, to wire and cable insulation, windshield system components and more. We talked to the PVC Guru to get all the answers every parent should know. Cancer is a major concern from exposure to vinyl chloride via inhalation, as vinyl chloride exposure has been shown to increase the risk of a rare form of liver cancer in humans. Proposition 65 NSRLs and MADLs Aug 15, 2013. Around the world, over 50% of PVC manufactured is used in construction. Pyrolytic products of PVC, of vinyl chloride and of plasticisers and stabilisers may irritate the respiratory organs, causing fibrosis, asthma, bronchitis and even cancer of the lung. In Polyvinyl Chloride Bis(2-ethylhexyl)Phathalate exist … Availability of Final Data Summaries and Priorities for Chemicals with Respect to Their Potential to Cause Birth Defects or Other Reproductive Harm; Cal EPA. ; Anything that may cause a normal body cell to develop abnormally potentially can cause cancer; general categories of cancer-related or causative agents are as follows: chemical or toxic compound exposures, ionizing radiation, some pathogens, and human genetics. Air Resources Board; Exposure to vinyl chloride occurs mainly in the workplace. In total, answers were obtained … PVC, or Polyvinyl Chloride, is a type of plastic used in millions of everyday items such as pipes, toys, carpet backing, bottles and credit cards. If degraded, can transfer plasticizers, some of which are toxic. * This data for Bis(2-ethylhexyl)Phthalate and Vinyl Chloride Monomer apply to the pure form of the compound. Cancer in Humans Vinyl chloride was evaluated in previous IARC Monographs (IARC, 1979 , 1987 2008) and ... polyvinyl chloride or poly-vinyl chloride products. It is also known as chloroethene, chloroethylene, ethylene monochloride, or monochloroethylene. Public Notices Related to this Chemical. PVC is used in an enormous range of domestic and industrial products, from raincoats and shower curtains to window frames and indoor plumbing. Please visit topics related to environmental health, safety, and toxicology on MedlinePlus, the NLM’s flagship website for health information for patients, families, and the general public.. The National Institute of Environmental Health Sciences (NIEHS) also offers related resources that may be of interest: [Note: Shipped as a liquefied compressed gas.] CANCER-SUSPECT AGENT IN THIS AREA. Uses [of PolyVinyl Chloride] Exposure to polyvinyl chloride dust was associated with an increased incidence of lung tumours in one study; the authors suggested that trapped vinyl chloride monomer was responsible [ref: 30]. Next to polyethylene, it is the most widely used plastic in the world. Personal Risks. About … Cancer: OEHHA 2013. Cancer is the uncontrolled growth of abnormal cells anywhere in a body. OEHHA 2009. EPA has classified vinyl chloride as a Group A, human carcinogen. In addition to reports that pertained to these cohorts in their entirety, several studies reported findings from individual Belongs to the Following … Updated 2011. PVC is very corrosive and abrasive and cutters that are not made from stainless steel or a comparably corrosive resistant material are likely to deteriorate over time. In terms of revenue generated, it is one of the most valuable products of the chemical industry. Langård S(1), Rosenberg J, Andersen A, Heldaas SS. Vinyl chloride is a colorless gas at normal temperatures. PVC was discovered accidentally in the early 19 th century when the polymer appeared as a white solid inside sunlight-exposed flasks of vinyl chloride. No relation was found between lung cancer and cumulative VCM exposure. Two of Polyvinyl Chloride s impurities are listed as carcinogens. Polyvinyl chloride, better known as PVC or vinyl, is an inexpensive plastic so versatile it has become completely pervasive in modern society.The list of products made from PVC is exhaustive, ranging from phonograph records to drainage and potable piping, water bottles, cling film, credit cards and toys. As a building material, PVC is cheap, durable, and easy to assemble. Vinyl chloride exists in liquid form if it is kept under high pressure or at low temperatures (less than -13.4�C). It is in such widespread usage due to its strength and resistance to sunlight, oil and chemicals, weathering and fire. Polyvinyl chloride, (IUPAC Polychloroethene) commonly abbreviated PVC, is a widely used thermoplastic polymer. Melanoma occurred in excess in one study [ref: 12] but has not been mentioned in others. Monomer* is an OSHA cancer suspect agent, ACGIH confirmed human carcinogen, and NTP and IARC human carcinogen. Testicular cancer has usually not been regarded to be an occu-pational disease. Author information: (1)National Hospital, Center for Occupational and Environmental Medicine, Oslo, Norway. Breathing vinyl chloride for long periods of time can result in permanent liver damage, immune reactions, nerve damage, and liver cancer. Work ers employed in PVC plants are at high risk with respect to PVC-induced lung disease. 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